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CBD dosage: Benefits, safety, and side effects

CBD is one of over 100 cannabinoids found in hemp and cannabis plants. CBD oil works with the body’s endocannabinoid system to produce a broad range of potentially beneficial effects. By indirectly influencing cannabinoid receptors, CBD can help the body make better use of the endocannabinoids produced in the body.

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The link between neuroinflammation and the endocannabinoid system, and in particular C2 receptors, suggests that there is potential for the use of CBD in the management of Parkinson's disease and hopefully future research will focus on this. While research on using CBD oil to reduce neuroinflammation in Parkinson’s patients is limited, there have been enough conclusive studies and clinical trials to support CBD oil as an effective anti-inflammatory agent.

The loss of muscle control is often the most distressing and complicated symptom of Parkinson’s disease to address. Dopamine is key in signaling the start of movement, passing information between the brain and body. Dopamine-producing neurons in the substantia nigra area of the brain are destroyed in Parkinson’s disease, resulting in a dopamine deficit of 60-80%.

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In a study performed on animal test subjects, researchers found cannabinoids, including CBD, inhibited the reuptake of dopamine, making more of the neurotransmitter available in the brain. Finally, a recent study found that CBD can work as an inverse agonist on the G-coupled protein receptor known as GPR6. A depletion in the GPR6 leads to a reduction in dopamine.

While all these results are promising, it’s important to keep in mind there’s still a significant lack of conclusive research specific to using CBD oil for Parkinson’s disease. As laws around cannabis in the U.S. (and beyond) continue to change, hopefully more clinical trials will be performed on humans with Parkinson’s, and answers will become clearer.

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The best CBD oil for managing Parkinson’s disease will depend on the needs of the patient. It is important to always buy high-quality CBD oil from a reputable brand. Here’s what to look out for when choosing a CBD oil for Parkinson’s disease: 1. Consider the source. Whenever possible, buy from a brand that sources their CBD from organically grown hemp.

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2. Read the label. Always read the ingredients list on any product before you buy. Look for brands that contain as few ingredients as possible. Typically, all a CBD oil needs to contain are cannabidiol (CBD) and a carrier oil like MCT oil, hemp seed, or coconut oil. Some full-spectrum products will contain terpenes, giving the oil a natural hemp flavor.

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3. Look for transparency. Reputable brands will be transparent with their process. They will third-party lab test their extractions for both purity and potency. These lab test results will be posted in a Certificate of Analysis (Co, A). These Co, As will give you a complete breakdown of everything that is or is not in your CBD oil.

CBD dosage: Benefits, safety, and side effects

4. Know the law. Before you make any CBD oil purchase, it is critical that you understand the laws in your state. While CBD oil with a THC content of 0. 3% or less is legal at a federal level, the final decision regarding CBD’s legality has been left up to the states.

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If you live in a state that has legalized recreational and medicinal cannabis, you should have no problem purchasing CBD oil. But states with more restrictive laws could limit your purchase options. Check out our state-by-state guide on cannabis laws in the U.S. for more information. Parkinson’s disease is a condition without a cure and as such, sometimes the traditional forms of treatment fall short.

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